drugset

drugset / Trial / NCT00987207

Pharmacological Postconditioning During the Aortic Valvular Surgery

NCT00987207 ↗

Phase 3 Completed 56 enrolled Hospices Civils de Lyon

RandomizedParallel-groupSingle-blindTreatment

Summary

Primary objective: To evaluate the efficacy of the cyclosporin A administration to induce a cardioprotection during the valvular surgery.

Timeline

Start: 2008-10
Primary completion: 2010-09
Completion: 2010-09

Publications

Results Chiari P, Angoulvant D, Mewton N, Desebbe O, Obadia JF, Robin J, Farhat F, Jegaden O, Bastien O, Lehot JJ, Ovize M. Cyclosporine protects the heart during aortic valve surgery. Anesthesiology. 2014 Aug;121(2):232-8. doi: 10.1097/ALN.0000000000000331.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cyclosporine	Peptide	2.5 mg/kg	Intravenous

Indications