Irbesartan Versus Amlodipine: The OBI Study

Summary

Objective: 1. To study the effectiveness of irbesartan 300mg and amlodipine 10 mg in 24h ambulatory blood pressure values in obese subjects 2. To study the drug specific effect in arterial stiffness 3. To study possible drug mechanisms in obesity (reduction of central adiposity and changing the ratio of leptin to adiponectin)

Timeline

Start

2012-01

Primary completion

2013-01

Completion

2014-01

Drugs

Indications