Study of the Effect of Individualizing Daytrana Wear-times on Sleep in Children With ADHD

Completed 26 enrolled Cox Health Systems

RandomizedCrossoverSingle-blindTreatment

Summary

Methylphenidate may improve sleep in children with ADHD. By leaving Daytrana (methylphenidate) patch for a longer time then 9 hours, many children report short sleep latencies and better quality of sleep.

Timeline

Start: 2009-12
Primary completion: 2011-02
Completion: 2011-02

Outcome

Missed primary endpoint

registry p = 0.588; Mean Difference (Final Values) 0.34 (95% CI 0 to 233); ANOVA NCT00989950 ↗

paper Patch wear time exerted no significant effect on sleep latency or total sleep time PMID 22115000 ↗

Publications

Results Ashkenasi A. Effect of transdermal methylphenidate wear times on sleep in children with attention deficit hyperactivity disorder. Pediatr Neurol. 2011 Dec;45(6):381-6. doi: 10.1016/j.pediatrneurol.2011.09.003.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Methylphenidate	Small molecule	10 mg	Other
Subject	Methylphenidate	Small molecule	30 mg	Other