drugset / Trial / NCT00992134

Immunochemotherapy With Rituximab-Bendamustine-Cytarabine (R-BAC) for Patients With Mantle Cell Lymphoma

NCT00992134 ↗

Phase 2 Completed 41 enrolled St. Bortolo Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The objective of the study is to demonstrate the safety, tolerability, and activity of Rituximab-Bendamustine-Cytarabine(R-BAC) regimen in patients with mantle cell lymphoma (MCL) aged 65 years or more, as well as in younger patients who are not eligible for intensive regimens including/not including autologous transplantation.

Timeline

Start
2009-06
Primary completion
2011-06
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 70 mg/m2 Intravenous
Subject Cytarabine Small molecule 800 mg/m2 Intravenous
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous

Indications