drugset / Trial / NCT00996723
Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)
Phase 1
Completed
25 enrolled
St. Jude Children's Research Hospital
AstraZeneca · collabThe Cure Starts Now Foundation · collabTyler's Treehouse · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a Phase I clinical trial evaluating the combination of vandetanib and dasatinib during and after radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG).
Timeline
- Start
- 2009-10
- Primary completion
- 2012-04
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Vandetanib | Small molecule | — | Oral |
| Subject | dasatinib anhydrous | Small molecule | — | Oral |