drugset / Trial / NCT01000246

Response to Influenza Virus Vaccination in Patients Immunocompromised Due to Chemotherapy

NCT01000246

Completed 50 enrolled St. Antonius Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

Patients treated with chemotherapy or immunosuppressives are at higher risk of influenza infection and mortality and morbidity are higher compared to healthy adults. Vaccination against the influenza virus can prevent these complications. In this study it is investigated whether vaccination during chemotherapy is effective in reaching protective serum antibody concentrations and the relation between time of vaccination (day 4 +/- 1 day versus day 16 +/- 1 day of the chemotherapy cycle).

Timeline

Start
2009-10
Primary completion
2009-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Influenza Virus Vaccine Vaccine 0.5 ml Intramuscular