drugset / Trial / NCT01004003

Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

NCT01004003

Phase 2 Completed 125 enrolled Boehringer Ingelheim
RandomizedParallel-groupOpen-labelTreatment

Summary

The study aim is to determine maximally tolerated dose (MTD) of BIBF 1120 in HCC (hepatocellular cancer) and compare efficacy of BIBF 1120 to Sorafenib in HCC patients

Timeline

Start
2009-10-22
Primary completion
2014-07-14
Completion
2016-10-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Nintedanib Small molecule 200 mg
Comparator Sorafenib Small molecule Oral