drugset / Trial / NCT01004081

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding

NCT01004081

Phase 2 Completed 54 enrolled Biogen
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the efficacy, safety and tolerability of 2 dosing regimens of BIIB021 in combination with exemestane in women whose HR+ breast cancer had progressed following treatment with a nonsteroidal aromatase inhibitor (AI).

Timeline

Start
2009-11
Primary completion
2011-10
Completion
2011-10

Drugs

EvaluationDrugModalityDoseRoute
Subject BIIB021 Small molecule 100 mg Oral
Subject BIIB021 Small molecule 450 mg Oral
Background Exemestane Small molecule 25 mg

Indications