Armodafinil in Binge Eating Disorder (BED)

Phase 3 Completed 60 enrolled Lindner Center of HOPE Cephalon · collab University of Cincinnati · collab

RandomizedSingle-groupQuadruple-blindTreatment

Summary

The purpose of this research study is to study the effectiveness, tolerability and safety of armodafinil in outpatients with binge eating disorder.

Timeline

Start: 2009-11
Primary completion: 2014-11
Completion: 2015-05

Outcome

Missed primary endpoint

paper In the primary longitudinal analysis, armodafinil and placebo produced similar rates of improvement in binge eating day frequency (the primary outcome measure); PMID 26011779 ↗

Publications

McElroy SL, Guerdjikova AI, Mori N, Blom TJ, Williams S, Casuto LS, Keck PE Jr. Armodafinil in binge eating disorder: a randomized, placebo-controlled trial. Int Clin Psychopharmacol. 2015 Jul;30(4):209-15. doi: 10.1097/YIC.0000000000000079.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Armodafinil	Small molecule	—	—