drugset / Trial / NCT01012232
Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration
RandomizedCrossoverQuadruple-blindTreatment
Summary
In a randomized, double-blind, cross-over trial, 48 patients scheduled for total knee arthroplasty with placement of an intracapsular catheter will be randomized to receive bolus injection of ropivacaine in high volume/low concentration (20 ml, 5 mg/mL) or low volume/high concentration (10 mL, 10 mg/mL) 6 and 24 hours postoperatively, and pain will be assessed at rest and with mobilization for 2 hours after injections.
Timeline
- Start
- 2009-06
- Primary completion
- 2009-10
- Completion
- 2009-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ropivacaine | Other / unclassified | 5 mg/ml | Other |
| Subject | Ropivacaine | Other / unclassified | 10 ml | Other |
| Subject | Ropivacaine | Other / unclassified | 10 mg/ml | Other |
| Subject | Ropivacaine | Other / unclassified | 20 ml | Other |
Indications
No indication recorded.