Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis

Summary

This phase I trial studies the side effects and best dose of arsenic trioxide with or without ascorbic acid in treating patients with myelofibrosis. Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving arsenic acid together with ascorbic acid may kill more cancer cells.

Timeline

Start

2010-04

Primary completion

2015-02

Completion

2015-02

Drugs

Indications