Desoximetasone Spray 0.05%, 0.25%; Dose Ranging Study

Summary

The objectives of this study are to evaluate the efficacy and safety of two dosing regimens of desoximetasone 0.05% and 0.25% topical sprays as compared to a vehicle spray in patients with moderate to severe plaque psoriasis.

Timeline

Start

2009-11

Primary completion

2010-05

Completion

2010-05

Outcome

Met primary endpoint

registry Desoximetasone 0.25% Twice Daily vs Vehicle Twice Daily; p = 0.0090; t-test, 1 sided NCT01018134 ↗

registry Desoximetasone 0.25% Once Daily vs Vehicle Once Daily; p = 0.0186; t-test, 1 sided; note: statistically significant difference between treatment groups NCT01018134 ↗

registry Desoximetasone 0.25% Twice Daily vs Vehicle Twice Daily; p = 0.0361; t-test, 1 sided; note: statistically significant difference between treatment groups NCT01018134 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Desoximetasone	Small molecule	0.05 %	Topical
Subject	Desoximetasone	Small molecule	0.25 %	Topical

Indications