drugset / Trial / NCT01018420
Pharmacokinetic and Exploratory Electrocardiogram (ECG) Study
RandomizedParallel-groupQuadruple-blindBasic science
Summary
This study will characterize the pharmacokinetics of colchicine after an oral dosing regimen of 4.8 mg over 6 hours. In addition it will compare the electrocardiogram (ECG) changes, if any, from this dosing regimen to that of a single dose of moxifloxacin 400 mg, a positive control for the corrected QT interval (QTc) prolongation.
Timeline
- Start
- 2007-11
- Primary completion
- 2007-12
- Completion
- 2008-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Colchicine | Small molecule | 0.6 mg | Oral |
| Comparator | Moxifloxacin | Small molecule | 400 mg | — |
Indications
No indication recorded.