Safety and Efficacy Study of Intravenous Uricase-PEG 20

Summary

The purpose of this study is to assess the safety, pharmacokinetics and pharmacodynamics of single intravenous doses of Uricase-PEG 20.

Timeline

Start

2009-10

Primary completion

2010-03

Completion

2010-03

Publications

• Background Bomalaski JS, Holtsberg FW, Ensor CM, Clark MA. Uricase formulated with polyethylene glycol (uricase-PEG 20): biochemical rationale and preclinical studies. J Rheumatol. 2002 Sep;29(9):1942-9.

Drugs

Indications