Dronabinol Naltrexone Treatment for Opioid Dependence

Summary

The goal of this two-year study is to test the efficacy of dronabinol as an adjunct to maintenance treatment with naltrexone in opioid-dependent individuals. We hypothesize that administering dronabinol during detoxification and during the first few weeks of naltrexone treatment will lead to improved naltrexone tolerability, resulting in better naltrexone compliance and treatment retention, and ultimately a reduction in opioid use and relapse rates.

Timeline

Start

2010-01

Primary completion

2012-12

Completion

2012-12

Drugs

Indications