drugset / Trial / NCT01025492
Study of Trilipix Effects on Lipids and Arteries
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Fibrates reduce atherosclerosis and cardiovascular disease events. A major mechanism of this benefit appears to be their ability to raise plasma high density lipoprotein cholesterol (HDL-C), especially in patients with high triglyceride levels. This study will investigate the effects of the addition of Trilipix (fenofibric acid) versus placebo to ongoing statin treatment on high density lipoprotein (HDL) composition and arterial function in subjects with insulin resistance.
Timeline
- Start
- 2009-11
- Primary completion
- 2011-03
- Completion
- 2011-03
Outcome
Outcome not reported
Stopped (Business): “Collaborator/corporate sponsor withdrew funding and permission to continue.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | ABT-335 | Small molecule | 135 mg | Oral |