drugset / Trial / NCT01025492

Study of Trilipix Effects on Lipids and Arteries

NCT01025492 ↗

Phase 4 Terminated 24 enrolled University of Utah Abbott · collab
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Fibrates reduce atherosclerosis and cardiovascular disease events. A major mechanism of this benefit appears to be their ability to raise plasma high density lipoprotein cholesterol (HDL-C), especially in patients with high triglyceride levels. This study will investigate the effects of the addition of Trilipix (fenofibric acid) versus placebo to ongoing statin treatment on high density lipoprotein (HDL) composition and arterial function in subjects with insulin resistance.

Timeline

Start
2009-11
Primary completion
2011-03
Completion
2011-03

Outcome

Outcome not reported

Stopped (Business): “Collaborator/corporate sponsor withdrew funding and permission to continue.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator ABT-335 Small molecule 135 mg Oral

Indications