drugset / Trial / NCT01025882

Margin-Intense Combo Therapy in Pts w/Potentially Resectable Pancreatic Cancer

NCT01025882 ↗

Phase 1 Terminated 5 enrolled University of Texas Southwestern Medical Center
Non-randomizedSingle-groupOpen-labelTreatment

Summary

RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue. Drugs used in chemotherapy, such as gemcitabine hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving stereotactic body radiation therapy together with gemcitabine hydrochloride may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects of stereotactic body radiation therapy when given with or without gemcitabine hydrochloride in treating patients with pancreatic cancer that can be removed by surgery.

Timeline

Start
2009-10
Primary completion
2011-02-18
Completion
2011-02-18

Outcome

Outcome not reported

Stopped: “DSMC closed due to patient deaths”

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule — Intravenous