drugset / Trial / NCT01029158
A Trial to Compare the Efficacy of Two Formulations of Avotermin Against Placebo
RandomizedSingle-groupDouble-blindBasic science
Summary
RN1006 has been developed as a stabilized formulation of avotermin which, when dosed once in pre-clinical studies in animals, has shown comparable scar improvement efficacy to the standard twice-dosed Juvista formulation. The aim of this trial is to investigate the efficacy of RN1006 compared to Juvista in a human volunteer model
Timeline
- Start
- 2009-08
- Primary completion
- 2010-09
- Completion
- 2010-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avotermin | Protein / enzyme biologic | 205 ng | Other |
| Subject | Avotermin | Protein / enzyme biologic | 250 ng | Other |
| Subject | Avotermin | Protein / enzyme biologic | 500 ng | Other |
Indications
No indication recorded.