drugset / Trial / NCT01029223

The Influence of Heart Rate Reduction Upon Central Arterial Pressure in Younger and Older Healthy Individuals

NCT01029223

Phase 4 Withdrawn 42 enrolled Bayside Health
RandomizedCrossoverQuadruple-blindBasic science

Summary

The purpose of this study is to determine the effect of slowing heart rate upon both central and peripheral blood pressures using a medication called Ivabradine which slows heart rate without affecting heart contraction, and to compare the effects of ivabradine to a traditional blood pressure lowering medication called metoprolol (which is a beta-blocker).

Timeline

Start
2008-10
Primary completion
2011-12
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ivabradine Small molecule
Subject Metoprolol Other / unclassified

Indications