drugset / Trial / NCT01030692
Rivastigmine and Huperzine A as Treatments for Cocaine Dependence
Phase 1
Completed
72 enrolled
Baylor College of Medicine
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blind
Summary
The purpose of this study is to determine the safety and effects of rivastigmine and huperzine A (HupA), potential treatments for cocaine abuse, when used before experimental administration of cocaine, on a number of physical and psychological measures.
Timeline
- Start
- 2009-01
- Primary completion
- 2014-06
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Huperzine A | Traditional medicine (herbal / TCM) | 0.4 mg | Oral |
| Comparator | Huperzine A | Traditional medicine (herbal / TCM) | 0.8 mg | Oral |
| Comparator | Rivastigmine | Small molecule | 3 mg | Oral |
| Comparator | Rivastigmine | Small molecule | 6 mg | Oral |