Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study
Summary
Evaluation of the safety, tolerability and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).
Timeline
- Start
- 2009-12
- Primary completion
- 2010-12
- Completion
- 2010-12
Outcome
Mixed primary results
registry Deoxycholic Acid Injection 1 mg/cm² vs Placebo; p = 0.052; Difference from placebo -0.3 (95% CI -0.61 to 0.00) NCT01032889 ↗
registry Deoxycholic Acid Injection 2 mg/cm² vs Placebo; p = 0.003; Difference from placebo -0.5 (95% CI -0.77 to -0.16) NCT01032889 ↗
registry Deoxycholic Acid Injection 1 mg/cm² vs Placebo; p = 0.117; Difference from placebo -0.2 (95% CI -0.55 to 0.06) NCT01032889 ↗
registry Deoxycholic Acid Injection 2 mg/cm² vs Placebo; p <0.001; Difference from placebo -0.6 (95% CI -0.91 to -0.30) NCT01032889 ↗
registry Deoxycholic Acid Injection 1 mg/cm² vs Placebo; p = 0.005; Difference from placebo -1.4 (95% CI -2.44 to -0.46) NCT01032889 ↗
registry Deoxycholic Acid Injection 2 mg/cm² vs Placebo; p <0.001; Difference from placebo -2.5 (95% CI -3.48 to -1.48) NCT01032889 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Deoxycholic acid injection | Unknown | 1 unknown | — |
| Subject | Deoxycholic acid injection | Unknown | 2 unknown | — |
Indications
No indication recorded.