The Effect Of PF-03654764 +/- Allegra On Symptoms Of Allergic Rhinitis

Summary

PF-03654764 should reduce the symptoms of allergic rhinitis. In this study patients will be exposed to pollen and their symptoms observed.

Timeline

Start

2010-01

Primary completion

2010-05

Completion

2010-05

Outcome

Missed primary endpoint

paper PF-03654764 + fexofenadine was not superior to pseudoephedrine + fexofenadine. PMID 25024716 ↗

Publications

• North ML, Walker TJ, Steacy LM, Hobsbawn BG, Allan RJ, Hackman F, Sun X, Day AG, Ellis AK. Add-on histamine receptor-3 antagonist for allergic rhinitis: a double blind randomized crossover trial using the environmental exposure unit. Allergy Asthma Clin Immunol. 2014 Jul 3;10(1):33. doi: 10.1186/1710-1492-10-33. eCollection 2014.

Drugs

Indications