Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery

Summary

This study will compare how well EXC 001 works to improve the appearance of scars in subjects undergoing breast scar revision surgery. The study will also evaluate the safety of EXC 001 in healthy adult subjects.

Timeline

Start

2009-12-22

Primary completion

2010-04-09

Completion

2010-04-09

Outcome

Met primary endpoint

registry analysis (superiority test); EXC 001 During Part B vs Placebo During Part B; p <0.001 NCT01037413 ↗

Publications

• Ghosh P, Dey A, Nandi S, Majumder R, Das S, Mandal M. CTGF (CCN2): a multifaceted mediator in breast cancer progression and therapeutic targeting. Cancer Metastasis Rev. 2025 Feb 13;44(1):32. doi: 10.1007/s10555-025-10248-4.

Drugs

Indications