drugset / Trial / NCT01037998
UFUR (Tegafur/Uracil) Plus Iressa in Non-small-cell Lung Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
Iressa \[epidermal growth factor tyrosine kinase inhibitor (EGFR-TKI)\] has been reported to activity against Non-small-cell Lung Cancer (NSCLC) failed previous chemotherapy. UFUR was found to have anti-angiogenesis effect when long term treatment was given. Combination of EGFR-TKI and anti-angiogenesis agents is a novel treatment.
Timeline
- Start
- 2005-11
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tegafur/Uracil | Unknown | 1 unknown | Oral |
| Comparator | Gefitinib | Small molecule | 250 mg | Oral |