drugset / Trial / NCT01037998

UFUR (Tegafur/Uracil) Plus Iressa in Non-small-cell Lung Cancer

NCT01037998

Phase 2 Completed 115 enrolled Taipei Veterans General Hospital, Taiwan
RandomizedParallel-groupOpen-labelTreatment

Summary

Iressa \[epidermal growth factor tyrosine kinase inhibitor (EGFR-TKI)\] has been reported to activity against Non-small-cell Lung Cancer (NSCLC) failed previous chemotherapy. UFUR was found to have anti-angiogenesis effect when long term treatment was given. Combination of EGFR-TKI and anti-angiogenesis agents is a novel treatment.

Timeline

Start
2005-11
Primary completion
2009-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tegafur/Uracil Unknown 1 unknown Oral
Comparator Gefitinib Small molecule 250 mg Oral