Safety and Efficacy Study of Intramuscular Uricase-PEG 20

Summary

The purpose of this study is to assess the safety, pharmacokinetics and pharmacodynamics of single and multiple intramuscular doses of Uricase-PEG 20

Timeline

Start

2009-12

Primary completion

2010-04

Completion

2010-05

Publications

• Background Bomalaski JS, Holtsberg FW, Ensor CM, Clark MA. Uricase formulated with polyethylene glycol (uricase-PEG 20): biochemical rationale and preclinical studies. J Rheumatol. 2002 Sep;29(9):1942-9.

Drugs

Indications