The Effect of Oral and Intravenous Ramosetron During Laparoscopic Cholecystectomy

Unknown 120 enrolled Seoul National University Bundang Hospital

RandomizedParallel-groupDouble-blindPrevention

Summary

Patients undergoing general anesthesia for laparoscopic cholecystectomy have a high risk of postoperative nausea and vomiting (PONV). The investigators investigated the effect of oral and IV ramosetron on PONV prophylaxis after laparoscopic cholecystectomy.

Timeline

Start: 2009-11
Primary completion: 2009-12
Completion: —

Publications

Ryu JH, Jeon YT, Hwang JW, Oh AY, Moon JY, Ro YJ, Kim CS, Chen C, Apfel CC, Do SH. Intravenous, oral, and the combination of intravenous and oral ramosetron for the prevention of nausea and vomiting after laparoscopic cholecystectomy: a randomized, double-blind, controlled trial. Clin Ther. 2011 Sep;33(9):1162-72. doi: 10.1016/j.clinthera.2011.07.018.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ramosetron	Small molecule	0.1 mg	Intravenous
Comparator	Ramosetron	Small molecule	0.3 mg	Intravenous

Indications

No indication recorded.