drugset / Trial / NCT01043926

Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017)

NCT01043926

Phase 1 Completed 16 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study will determine whether the plasma concentration-time profile and pharmacokinetics (PK) of suvorexant (MK-4305) in participants with moderate and mild hepatic insufficiency are similar to those observed in healthy participants.

Timeline

Start
2010-02-22
Primary completion
2010-04-14
Completion
2010-04-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Suvorexant Small molecule 20 mg

Indications