Oral Glutathione Supplementation on the Levels of Blood Glutathione

Completed 61 enrolled Milton S. Hershey Medical Center

RandomizedParallel-groupDouble-blindBasic science

Summary

This trial is designed to provide evidence of the efficacy of glutathione supplementation and health(GSH) and includes the assessment of both short term and long term effects. Based on previous laboratory animal studies and clinical data, the investigators anticipate that the effects of oral GSH supplementation will be progressive and cumulative. The study will also allow for the evaluation of effects of withdrawal of the supplement on the outcome variables.

Timeline

Start: 2010-02
Primary completion: 2011-09
Completion: 2014-10

Publications

Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015 Mar;54(2):251-63. doi: 10.1007/s00394-014-0706-z. Epub 2014 May 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Glutathione	Peptide	125 mg	Oral
Subject	Glutathione	Peptide	500 mg	Oral

Indications

No indication recorded.