Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.

Summary

Preterm birth is the leading cause of neonatal death and a significant cause of life long disability and health problems. It has been shown that the drug 17-hydroxyprogesterone caproate can help reduce the risk of preterm delivery in women with certain risk factors for preterm birth. We hope to learn whether this same medication can be used to prolong pregnancy in a group of patients in whom this medication has not been previously studied. Specifically, we hope to learn whether progesterone supplementation will delay delivery in women with pre-term, premature rupture of membranes (PPROM).

Timeline

Start

2010-02

Primary completion

2015-12

Completion

2015-12

Drugs

Indications