drugset / Trial / NCT01052090
Safety and Efficacy Study in Hepatitis C Patients With PHN121
Non-randomizedFactorialOpen-labelTreatment
Summary
To evaluate the safety, tolerability and efficacy of escalating dose of PHN121 when administered orally in non-responder hepatitis C genotype 1 patients
Timeline
- Start
- 2009-09
- Primary completion
- 2013-11
- Completion
- 2013-12
Publications
- Background Dai CY, Chuang WL, Huang JF, Hsieh MY, Yu ML. Rapid virological response in hepatitis C virus genotype 1 and early ribavirin exposure. Hepatology. 2008 Aug;48(2):692-3; author reply 693-4. doi: 10.1002/hep.22409. No abstract available.
- Background Huang JF, Dai CY, Lin YY, Yu ML, Liu SF, Lin IL, Hsieh MY, Lee LP, Lin ZY, Chen SC, Hsieh MY, Chang WY, Chuang WL. Performance characteristics of a real-time RT-PCR assay for quantification of hepatitis C virus RNA in patients with genotype 1 and 2 infections. Clin Chem Lab Med. 2008;46(4):475-80. doi: 10.1515/CCLM.2008.082.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PHN121 | Traditional medicine (herbal / TCM) | 2.91 g | Oral |
| Subject | PHN121 | Traditional medicine (herbal / TCM) | 4.85 g | Oral |
| Subject | PHN121 | Traditional medicine (herbal / TCM) | 7.77 g | Oral |