Study of Tranilast Alone or in Combination With Allopurinol in Subjects With Hyperuricemia

Summary

This is a randomized, double-blind, 3-period 3-treatment crossover followed by a 2-period 2-treatment crossover, phase 2 study in patients with documented hyperuricemia to evaluate the effect of tranilast on allopurinol pharmacokinetics (PK) and pharmacodynamics (PD) and to evaluate the effect of allopurinol on tranilast PK and PD as measured by reduction in serum uric acid levels.

Timeline

Start

2010-01

Primary completion

2010-06

Completion

2010-11

Drugs

Indications