Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma

Summary

This phase I/II trial studies the side effects and best dose of lenalidomide and to see how well it works in treating patients with acquired immunodeficiency syndrome (AIDS)-related Kaposi sarcoma (KS). Lenalidomide may stop the growth of tumor cells by blocking blood flow to the tumor.

Timeline

Start

2010-08-27

Primary completion

2014-08-04

Completion

2014-08-04

Publications

• Reid EG, Shimabukuro K, Moore P, Ambinder RF, Bui JD, Han S, Martinez-Maza O, Dittmer DP, Aboulafia D, Chiao EY, Maurer T, Baiocchi R, Mitsuyasu R, Wachsman W; AIDS Malignancy Consortium (AMC). AMC-070: Lenalidomide Is Safe and Effective in HIV-Associated Kaposi Sarcoma. Clin Cancer Res. 2022 Jun 13;28(12):2646-2656. doi: 10.1158/1078-0432.CCR-21-0645.

Drugs

Indications