drugset / Trial / NCT01057654
A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatin
RandomizedParallel-groupQuadruple-blindBasic science
Summary
Lifibrol is a new lipid-lowering drug which lowers cholesterol to an extent in the order of magnitude of the statins. The mechanism of action of this compound is different from the one of statins but remains unknown. The current study will investigate the mechanism of action using stable-isotope turnover methods. The study will be done in healthy male volunteers.
Timeline
- Start
- 1996-01
- Primary completion
- 1996-04
- Completion
- 1998-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lifibrol | Small molecule | 600 mg | — |
| Comparator | Pravastatin | Small molecule | 40 mg | — |