drugset / Trial / NCT01059591
First Study in Humans With GSK424887
RandomizedCrossoverDouble-blindBasic science
Summary
This is the first study in Humans with GSK424887 to evaluate what effects, good or bad, the drug has on human health (safety and tolerability) and the amount of drug which gets into the bloodstream and is eliminated from the body (pharmacokinetics). Also the study aims to investigate the penetration of the drug in the human brain by using PET (Positron Emission Tomography) imaging technology
Timeline
- Start
- 2006-05-25
- Primary completion
- 2007-01-25
- Completion
- 2007-01-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK424887 | Small molecule | 2 mg | — |
| Subject | GSK424887 | Small molecule | 10 mg | — |
| Subject | GSK424887 | Small molecule | 50 mg | — |
| Subject | GSK424887 | Small molecule | 100 mg | — |