drugset / Trial / NCT01059851

Pharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)

NCT01059851

Phase 1 Completed 16 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study will investigate whether the plasma concentration-time profile and pharmacokinetics (PK) of suvorexant (MK-4305) in participants with impaired renal function are similar to those observed in healthy participants; and will evaluate the safety and tolerability of suvorexant both in participants with impaired renal function and in healthy participants.

Timeline

Start
2010-05-24
Primary completion
2010-07-15
Completion
2010-07-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Suvorexant Small molecule 20 mg Oral

Indications