drugset / Trial / NCT01061333

Early Airway Response to Allergen in Asthmatics (MK-0000-176)

NCT01061333

Phase 1 Completed 16 enrolled Merck Sharp & Dohme LLC
RandomizedCrossoverDouble-blindTreatment

Summary

This study will assess the Early Airway Response (EAR) associated change in forced expiratory volume in one second (FEV1) and plasma 9α-11ß-PGF2 ('9P') after single dose pretreatment of nedocromil, montelukast, and mometasone.

Timeline

Start
2010-06
Primary completion
2011-02
Completion
2011-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Mometasone Other / unclassified 400 ug Inhaled
Subject Montelukast Other / unclassified 10 mg Oral
Subject Nedocromil Small molecule 4 mg Inhaled

Indications