drugset

drugset / Trial / NCT01062165

Effect of Weight and/or Obesity on Caspofungin Drug Concentrations

NCT01062165 ↗

Phase 4 Completed 18 enrolled Texas Tech University Health Sciences Center National Center for Research Resources (NCRR) · collab University of Texas Southwestern Medical Center · collab

NaSingle-groupOpen-label

Summary

This study will find how weight affects the dosing of a drug called caspofungin. Currently, the amount of caspofungin a patient receives is the same regardless of the patient's weight.

Timeline

Start: 2010-02
Primary completion: 2010-12
Completion: 2010-12

Publications

Results Hall RG 2nd, Swancutt MA, Meek C, Leff R, Gumbo T. Weight drives caspofungin pharmacokinetic variability in overweight and obese people: fractal power signatures beyond two-thirds or three-fourths. Antimicrob Agents Chemother. 2013 May;57(5):2259-64. doi: 10.1128/AAC.01490-12. Epub 2013 Mar 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Caspofungin	Other / unclassified	70 mg	Intravenous

Indications