drugset / Trial / NCT01064726

A Study To Explore The Effect On Inflammatory Markers After Nasal Allergen Challenge In Subjects With Seasonal Allergic Rhinitis And The Effect Of A Single Dose Of Ibuprofen Or Fluticasone Propionate On The Allergen Response.

NCT01064726

Phase 1 Completed 18 enrolled Pfizer
RandomizedCrossoverDouble-blindTreatment

Summary

After a nasal allergen challenge it should be possible to measure markers of inflammation that may be useful to assess the properties of future drugs. If these markers are reproducible and impacted by the study drugs they could be useful for future drug development.

Timeline

Start
2009-10
Primary completion
2010-04
Completion
2010-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluticasone propionate Other / unclassified 200 ug Intranasal
Subject Ibuprofen Small molecule 800 mg Oral

Indications