drugset / Trial / NCT01066104
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis
RandomizedParallel-groupTriple-blindTreatment
Summary
The investigators are doing this research study to learn more about a drug called Xolair (omalizumab). The investigators want to see if it is an effective treatment for chronic rhinosinusitis (CRS). Specifically, the investigators want to see whether Xolair will make nasal polyps smaller and less thick, and relieve symptoms in people with CRS. Polyps are abnormal growths of tissue that can grow in the lining of your sinuses (the inside of your nose). The investigators also want to find out if it is safe to use (whether it causes side effects).
Timeline
- Start
- 2009-12
- Primary completion
- 2015-07
- Completion
- 2015-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Omalizumab | Monoclonal antibody | 150 mg | Subcutaneous |
| Comparator | Omalizumab | Monoclonal antibody | 375 mg | Subcutaneous |