drugset

drugset / Trial / NCT01066585

A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation

NCT01066585 ↗

Phase 3 Completed 410 enrolled Topaz Pharmaceuticals Inc

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine if 0.5% Ivermectin Cream is a safe and effective treatment for head lice infestations.

Timeline

Start: 2010-03
Primary completion: 2010-06
Completion: 2010-07

Outcome

Met primary endpoint

paper day 15 (73.8% vs. 17.6%) (P<0.001 for each comparison). PMID 23113480 ↗

Publications

Pariser DM, Meinking TL, Bell M, Ryan WG. Topical 0.5% ivermectin lotion for treatment of head lice. N Engl J Med. 2012 Nov 1;367(18):1687-93. doi: 10.1056/NEJMoa1200107.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ivermectin	Small molecule	0.5 %	Topical

Indications