drugset / Trial / NCT01068782
Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse
RandomizedParallel-groupOpen-labelTreatment
Summary
This study was conducted in subjects with grade IV astrocytic tumors (a type of cancer that can occur in the brain or spinal cord) in first or second relapse.
Timeline
- Start
- 2010-04
- Primary completion
- 2011-05
- Completion
- 2013-10
Outcome
Outcome not reported
Stopped (Enrollment): “Enrollment in this study was terminated for business development reasons before completing one third of the expected subject population, no formal statistical testing was performed.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cabozantinib | Small molecule | 25 mg | Oral |
| Subject | Cabozantinib | Small molecule | 50 mg | Oral |
| Subject | Cabozantinib | Small molecule | 75 mg | Oral |
| Subject | Cabozantinib | Small molecule | 125 mg | Oral |