drugset / Trial / NCT01068782

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

NCT01068782 ↗

Phase 2 Terminated 19 enrolled Exelixis
RandomizedParallel-groupOpen-labelTreatment

Summary

This study was conducted in subjects with grade IV astrocytic tumors (a type of cancer that can occur in the brain or spinal cord) in first or second relapse.

Timeline

Start
2010-04
Primary completion
2011-05
Completion
2013-10

Outcome

Outcome not reported

Stopped (Enrollment): “Enrollment in this study was terminated for business development reasons before completing one third of the expected subject population, no formal statistical testing was performed.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 25 mg Oral
Subject Cabozantinib Small molecule 50 mg Oral
Subject Cabozantinib Small molecule 75 mg Oral
Subject Cabozantinib Small molecule 125 mg Oral

Indications