drugset / Trial / NCT01070485

BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease

NCT01070485

Phase 2 Completed 23 enrolled Bayer
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of the study is to investigate if multiple (up to four) intravenous injections of Xofigo (Alpharadin) have any clinically relevant effect on bone markers in breast cancer patients with bone dominant disease who have progressed on endocrine therapy and are no longer considered suitable for endocrine therapy. In addition the safety of Xofigo (Alpharadin) will be assessed.

Timeline

Start
2010-01
Primary completion
2011-03
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Radium-223 dichloride Other / unclassified 0.05 mbq/kg Intravenous