drugset / Trial / NCT01071525
The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker
Non-randomizedSingle-groupOpen-labelTreatment
Summary
1. Treatment of Hypercholesterolemic patients with niacin will cause a significant decrease in oxidative stress and a decrease in the atherogenecity in blood samples of the patients. 2. A possible correlation between oxidative stress in hypercholesterolemic patients taking niacin to clinical hypercholesterolemia parameters is possible. 3. Using a novel biomarker will enable a precise detection of the change in the oxidative stress in hypercholesterolemic patients.
Timeline
- Start
- 2010-04
- Primary completion
- 2010-08
- Completion
- 2010-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Niacin | Small molecule | — | — |
| Comparator | laropiprant | Small molecule | — | — |