drugset

drugset / Trial / NCT01072734

Auto-immunity in Lupus Patients After Influenza Vaccine

NCT01072734 ↗

Phase 2 Completed 28 enrolled Assistance Publique - Hôpitaux de Paris Institut National de la Santé Et de la Recherche Médicale, France · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

Annual influenza vaccination is recommended in patients with systemic lupus erythematosus (SLE). However some concerns remain about vaccination and the risk of lupus flare

Timeline

Start: 2009-09
Primary completion: 2010-01
Completion: 2010-02

Publications

Launay O, Paul S, Servettaz A, Roguet G, Rozenberg F, Lucht F, Lambert C, Presles E, Goulvestre C, Meritet JF, Galtier F, Dubray C, Lebon P, Weill B, Batteux F. Control of humoral immunity and auto-immunity by the CXCR4/CXCL12 axis in lupus patients following influenza vaccine. Vaccine. 2013 Aug 2;31(35):3492-501. doi: 10.1016/j.vaccine.2013.05.095. Epub 2013 Jun 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Influenza Virus Vaccine	Vaccine	—	—

Indications