drugset / Trial / NCT01080963

Daptomycin as Antibiotic Prophylaxis of Sternal Wound Infections

NCT01080963

Phase 4 Completed 650 enrolled Hannover Medical School Novartis · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to show that the incidence of sternal wound infections at day 30 after cardiac surgery is 50% lower with the additional use of Daptomycin on top of a standard antibiotic prophylaxis as compared to the standard antibiotic prophylaxis alone.

Timeline

Start
2008-11
Primary completion
2012-03
Completion
2012-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cefuroxime Small molecule 1500 mg Intravenous
Comparator Daptomycin Other / unclassified 350 mg

Indications