Identifying the Effect of Somatostatin Treatment in Early Postoperative Simple Small Bowel Obstruction

Summary

Primary Objective: To demonstrate whether an early fixed Somatostatin treatment improves the complete recovery rate of early postoperative simple small bowel obstruction (EPSSBO) compared with the common daily practice Notes: 1. complete recovery= toleration of solid food+ flatus+ passage+ recovery of bowel movement. 2. common daily practice includes: * NPO (Nil per mouth), re-dehydration, TPN (Total Parenteral Nutrition) if needed. Check \& make sure stability of electrolytes daily. * GI (Gastro-Intestinal) depression via NGT (Naso-Gastric Tube) * Discontinue opiates, instead of NSAIDs. (Non-Steroidal Anti-Inflammatory Drugs) * Pro-dynamic drugs or other drugs which may interfere with GI (Gastro-Intestinal) movement eg. anti-histamines, anti-cholinergic, opiates, anti-depressives are not indicated. Secondary Objectives: To investigate whether an early fixed Somatostatin treatment will bring much benefit to EPSSBO pts compared with the common daily practice,for this purpose,the study will investigate the endpoints below.

Timeline

Start

2009-06

Primary completion

2010-11

Completion

2010-11

Drugs

Indications