drugset / Trial / NCT01083485
OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to demonstrate that treatment with OXN PR tablets is non inferior to treatment with OXY PR tablets in terms of analgesic efficacy in patients with postoperative pain after knee arthroplasty based on average pain intensity scores.
Timeline
- Start
- 2010-03
- Primary completion
- 2010-10
- Completion
- 2010-11
Outcome
Met primary endpoint
registry Mean Difference (Final Values) -0.1 (95% CI -0.5 to 0.3); ANCOVA; note: A P value was not part of the analysis plan. NCT01083485 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naloxone | Small molecule | 5 mg | — |
| Subject | Naloxone | Small molecule | 10 mg | — |
| Comparator | Oxycodone | Other / unclassified | 10 mg | — |
| Comparator | Oxycodone | Other / unclassified | 20 mg | — |
Indications
No indication recorded.