drugset / Trial / NCT01085123

Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers

NCT01085123

Phase 1 Completed 10 enrolled AstraZeneca
Non-randomizedSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to determine the central 5-HT1B receptor occupancy of ZOMIG® Rapimelt (zolmitriptan) in healthy male volunteers.

Timeline

Start
2010-05
Primary completion
2010-10
Completion
2010-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Zolmitriptan Small molecule 2.5 mg Oral
Subject Zolmitriptan Small molecule 5 mg Oral
Subject Zolmitriptan Small molecule 10 mg Oral
Subject [11C]AZ10419369 Unknown Intravenous

Indications