drugset / Trial / NCT01088581

Adjuvant Hepatic Arterial Infusional Chemotherapy After Curative Resection of Hepatocellular Carcinoma

NCT01088581 ↗

Phase 3 Completed 101 enrolled Yonsei University
RandomizedParallel-groupDouble-blindTreatment

Summary

Several adjuvant therapies have been attempted to reduce uni-centric, and intra- or extrahepatic recurrence after curative surgical resection for hepatocellular carcinoma (HCC). However, because the efficacy of such adjuvant therapy remains unclear, there is no standard postoperative therapy. The investigators investigated whether adjuvant hepatic arterial infusional chemotherapy with 5-fluorouracil (5-FU) and cisplatin reduces the recurrence of HCC after curative resection.

Timeline

Start
2006-01
Primary completion
2007-12
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified — Other
Subject fluorouracil Small molecule — Other