drugset / Trial / NCT01091116
A Locally Injected Bradykinin Antagonist for TReatment of OSteoarthritiS
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether intra-articular (knee joint) administration of MEN16132 is effective reducing the pain from knee osteoarthritis.
Timeline
- Start
- 2010-03
- Primary completion
- 2011-02
- Completion
- 2011-03
Outcome
Missed primary endpoint
registry analysis (superiority or other test); Low Dose vs Mid Dose vs High Dose vs Single High Dose vs Placebo; p = 0.5263; ANCOVA NCT01091116 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fasitibant | Small molecule | 0.125 mg | Other |
| Subject | Fasitibant | Small molecule | 0.25 mg | Other |
| Subject | Fasitibant | Small molecule | 0.5 mg | Other |